These results demonstrate that measurement of blood viscosity during the coagulation process offers a number of potentially useful parameters. The MCV was significantly lower at a SR of 80 sec −1 versus 40 sec −1 ( P = 0.027) and the CLH significantly ( P = 0.048) increased for increasing SR. The TGP significantly ( P = 0.0023) shortened for increasing SR, and was significantly associated with the activated partial thromboplastin time at a SR of 20 sec −1 ( P = 0.038) and 80 sec −1 ( P = 0.019).
On the basis of the time‐dependent changes in blood viscosity, we identified the gel point (GP), the time‐to‐gel point (TGP), the maximum clot viscosity (MCV), and the clot lysis half‐time (CLH). For each subject, three consecutive measurements were performed, at a SR of 20, 40, 80 sec −1. In this study, we investigated the viscosity changes of whole blood in 10 subjects with a normal coagulation profile, using a cone‐on‐plate viscosimeter. These changes are reflected by changes in blood viscosity however, blood viscosity at different shear rates (SR) has not been previously explored during the coagulation process.
During the coagulation process, blood changes from a liquid to a solid gel phase.
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